MCPMod: An R Package for the Design and Analysis of Dose-Finding Studies
نویسندگان
چکیده
This vignette is an updated version of Bornkamp, Pinheiro, and Bretz (2009) and describes the MCPMod package for the R programming environment. The package implements a methodology for the design and analysis of dose-response studies that combines aspects of multiple comparison procedures and modeling approaches (Bretz, Pinheiro, and Branson 2005). The package provides tools for the analysis of dose finding trials, as well as a variety of tools necessary to plan an experiment to be analysed using the MCP-Mod methodology.
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برآورد دوزهای هدف با استفاده از روش MCPMod در مطالعات دوز-پاسخ
Background and Objective: Determining adequate model and estimation of target dose with high precision is a key goal in dose-response studies. MCPMod is a new method that used for model selection and estimation of target doses and unlike other methods it does not have any limitation. In this method, selection of models has performed by hypothesis testing also increasing responses that are a cr...
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